Prof. Dr. Jörg Enderlein
The lecture will introduce into the field of single-molecule fluorescence spectroscopy, starting from the physical basics, and then presenting various spectroscopic techniques. In particular, the lecture will discuss in detail fluorescence correlation spectroscopy (FCS), one of the most powerful tools in single-molecule studies. It will be explained how FCS can be used for measuring the size of molecules, their rotational diffusion, their interaction (e.g. binding/unbinding), conformational changes in large biomolecules (proteins, DNA), or the stoichiometry of molecular complexes.
Major Research Interests
Single molecule fluorescence spectroscopy and imaging, protein conformational dynamics and folding.