Workshop Small animal MRI
Prof. Dr. Susann Boretius
Professor of Functional Imaging. Head of the Functional Imaging Laboratory at the German Primate Center
Major Research Interests
Magnetic resonance imaging (MRI) and spectroscopy (MRS) - Neurosciences: basic and translational research
Our research is focused on the development and improvement of magnetic resonance (MR) methods for application in basic biomedical and applied clinical research especially in the fields of neurosciences. We are particularly interested in applying this method on experimental animals, but we do complementary studies in humans as well. As truly non-invasive techniques, MRI and MRS are important methods for translational research, because almost the same methods can be applied in animals and humans. In this context, our research and development activities aim to continuously improve the spatial and temporal resolution of MRI and MRS in rodents, in non-human primates and in humans. With the help of these techniques we are "watching" the brain while it thinks and aiming to better understanding what's happen with the brain during maturation and aging, and under healthy and pathological conditions as well. Moreover, by using appropriate animal models and more advanced contrast mechanism like diffusion based techniques, magnetization transfer and susceptibility mapping our goal is to increase the sensitivity and specificity of these MR methods for more precise diagnostics and for a more specific and early detection of the response to therapeutic intervention.